2-[(3-amino-2-pyridyl) amino]-1-ethanol is an organic compound with the chemical formula C7H10N4O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-[(3-Amino-2-pyridyl) amino]-1-ethanol is a colorless or pale yellow solid.
-Solubility: It is soluble in water, alcohol and acid.
Use:
- 2-[(3-Amino-2-pyridyl) amino]-1-ethanol is a chemical intermediate commonly used in organic synthesis reactions.
-It is also used to study the synthesis and properties of drugs, with potential medical applications.
Preparation Method:
2-[(3-amino-2-pyridyl) amino]-1-ethanol can be prepared in a variety of ways, the following is a common synthetic route:
1. 2-pyridinone formate was prepared by dissolving 2-pyridinamine in dichloromethane and adding benzoyl chloride.
2. Add 2-pyridone formate to dimethyl sulfoxide and ammonia solution, and react at low temperature.
3. Add acetic acid, and then purify by distillation and crystallization to obtain the product of 2-[(3-amino-2-pyridyl) amino]-1-ethanol.
Safety Information:
- 2-[(3-Amino-2-pyridyl) amino]-1-ethanol is a chemical substance, so it needs to be handled properly and follow safe operating procedures.
-Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-It may be irritating to the eyes, skin and respiratory system and should be avoided when in contact.
-During operation, ensure adequate ventilation. In the case of accidental spills, appropriate measures should be taken to remove contaminants.